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Other uses|Addiction (disambiguation)seealso2| Substance dependence (drug addiction)| Behavioral addiction Addiction is the continued use of a controlled substance|mood altering substance or behaviour despite adverse consequences,cite journal | author = Angres DH, Bettinardi-Angres K | title = The disease of addiction: origins, treatment, and recovery | journal = Dis Mon | volume = 54 | issue = 10 | pages = 696–721 | year = 2008 | month = October | pmid = 18790142 | doi = 10.1016/j.disamonth.2008.07.002 | url = or a neurological impairment leading to such behaviors.cite journal | author = American Society for Addiction Medicine | title = Definition of Addiction | journal = | volume = | issue = | pages = | year = 2012 | month = | url = http://www.asam.org/for-the-public/definition-of-addiction
Addictions can include, but are not limited to, alcohol abuse , drug abuse , exercise abuse, and gambling . Classic hallmarks of addiction include: impaired control over substances/behavior, preoccupation with substance/behavior, continued use despite consequences, and denial.cite journal | author = Morse RM, Flavin DK | title = The definition of alcoholism. The Joint Committee of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism | journal = JAMA | volume = 268 | issue = 8 | pages = 1012–4 | year = 1992 | month = August | pmid = 1501306 | doi = 10.1001/jama.268.8.1012| url = Habits and patterns associated with addiction are typically characterized by immediate gratification (short-term reward), coupled with delayed deleterious effects (long-term costs).cite journal | author = Marlatt GA, Baer JS, Donovan DM, Kivlahan DR | title = Addictive behaviors: etiology and treatment | journal = Annu Rev Psychol | volume = 39 | issue = | pages = 223–52 | year = 1988 | pmid = 3278676 | doi = 10.1146/annurev.ps.39.020188.001255 Physiological dependence occurs when the body has to adjust to the substance by incorporating the substance into its 'normal' functioning.cite journal | author = Torres G, Horowitz JM | title = Drugs of abuse and brain gene expression | journal = Psychosom Med | volume = 61 | issue = 5 | pages = 630–50 | year = 1999 | pmid = 10511013 | doi = This state creates the conditions of drug tolerance|tolerance and withdrawal . Tolerance is the process by which the body continually adapts to the substance and requires increasingly larger amounts to achieve the original effects. Withdrawal refers to physical and psychological symptoms people experience when reducing or discontinuing a substance the body had become dependent on. Symptoms of withdrawal generally include but are not limited to anxiety , irritability , intense craving (withdrawal)|craving s for the substance, nausea , hallucinations , headaches , cold sweats, and tremors .
Substance dependence
Main|Substance dependenceSubstance dependence can be diagnosed with Physical dependence|physiological dependence , evidence of tolerance or withdrawal, or without physiological dependence. DSM-IV substance dependencies include:
303.90 Alcohol dependence
304.00 Opioid dependence
304.10 Sedative , hypnotic , or anxiolytic dependence (including benzodiazepine dependence and barbiturate dependence )
Main|Behavioral addiction|Addictive behaviorThe term addiction is also sometimes applied to compulsions that are not substance-related, such as compulsive shopping, sex addiction/compulsive sex, overeating, problem gambling, exercise/sport and computer addiction . In these kinds of common usages, the term addiction is used to describe a recurring compulsive behavior|compulsion by an individual to engage in some specific activity, despite harmful consequences, as deemed by the user themselves to their individual health, mental state, or social life. There may be biological and psychological factors contributing to these addictions.Cite document | author = Pargman D, Burgess S | title = Hooked on Exercise: A Psycho-Biological Explanation | work=1977 Annual Meeting of North American Society for the Psychology of Sport and Physical Activity | year = 1977 | oclc = 425154924
Biological mechanisms
Research indicates that biological mechanisms are present. There are many varitables that have the studies in wide disagreement over the contributing factors. One example widely excepted, but not limited to is family history. Genetics, DNA, other mental health disorder can remain dormant for generations. The treatment providers have differing opinions on this issue commonly called Nature vs: Nuture
Personality theories of addiction
Role of affect dysregulation in addiction
Research has consistently shown strong associations between affective disorders and substance use disorders . Specifically, people with mood disorders are at increased risk of substance use disorders.cite journal | author = Cheetham A, Allen NB, Yücel M, Lubman DI | title = The role of affective dysregulation in drug addiction | journal = Clin Psychol Rev | volume = 30 | issue = 6 | pages = 621–34 | year = 2010 | month = August | pmid = 20546986 | doi = 10.1016/j.cpr.2010.04.005 | url = Affect and addiction can be related in a variety of ways as they play a crucial role in influencing motivated behaviours. For instance, affect facilitates action, directs attention, prepares the individual for a physical response, and guides behaviour to meet particular needs.cite journal | author = Gross JJ | title = The emerging field of emotion regulation: An integrative review | journal = Review of General Psychology | year = 1998 | month = September | volume = 2 | issue = 3 | pages = 271–299 | doi = 10.1037/1089-2680.2.3.271 Moreover, affect is implicated in a range of concepts relevant to addiction: negative reinforcement and positive reinforcement , behaviour motivation , regulation of cognition and Mood (psychology)|mood , and reasoning and decision making .cite journal | author = Bechara A, Damasio H | title = Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences | journal = Neuropsychologia | volume = 40 | issue = 10 | pages = 1675–89 | year = 2002 | pmid = 11992656 | doi =10.1016/S0028-3932(02)00015-5 cite journal | author= Quirk SW| title = Emotion concepts in models of substance abuse | journal = Drug and Alcohol Review | year = 2009 | month = May | volume = 20 | issue = 1 | pages = 95–104 | doi = 10.1080/09595230125185 Emotion-motivated reasoning has been shown to influence addictive behaviours via selecting outcomes that minimize negative affective states while maximizing positive affective states.cite journal | author = Westen D, Blagov PS, Harenski K, Kilts C, Hamann S | title = Neural bases of motivated reasoning: an FMRI study of emotional constraints on partisan political judgment in the 2004 U.S. Presidential election | journal = J Cogn Neurosci | volume = 18 | issue = 11 | pages = 1947–58 | year = 2006 | month = November | pmid = 17069484 | doi = 10.1162/jocn.2006.18.11.1947
Negative affect
The relationship between negative affect and substance use disorders has been the most widely studied model of addiction. It proposes that individuals who experience the greatest levels of negative affect are at the greatest risk of using substances/behaviours as a coping mechanism.cite journal | author = McCollam JB, Burish TG, Maisto SA, Sobell MB | title = Alcohol's effects on physiological arousal and self-reported affect and sensations | journal = J Abnorm Psychol | volume = 89 | issue = 2 | pages = 224–33 | year = 1980 | month = April | pmid = 7365134 | doi =10.1037/0021-843X.89.2.224 cite journal | author = Measelle JR, Stice E, Springer DW | title = A prospective test of the negative affect model of substance abuse: moderating effects of social support | journal = Psychol Addict Behav | volume = 20 | issue = 3 | pages = 225–33 | year = 2006 | month = September | pmid = 16938060 | pmc = 1560098 | doi = 10.1037/0893-164X.20.3.225 Here, substances and behaviours are used to improve mood and distract from unpleasant feelings. Once physical dependence has been established, substance abuse is primarily motivated by a desire to avoid negative affective states associated with withdrawal. Individuals high in affective mood disorders ( anxiety ) most commonly report high levels of negative affect associated with craving (withdrawal)|craving s.cite journal | author = Childress AR, Ehrman R, McLellan AT, MacRae J, Natale M, O'Brien CP | title = Can induced moods trigger drug-related responses in opiate abuse patients? | journal = J Subst Abuse Treat | volume = 11 | issue = 1 | pages = 17–23 | year = 1994 | pmid = 8201629 | doi =10.1016/0740-5472(94)90060-4 cite journal | author = Cooney NL, Litt MD, Morse PA, Bauer LO, Gaupp L | title = Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men | journal = J Abnorm Psychol | volume = 106 | issue = 2 | pages = 243–50 | year = 1997 | month = May | pmid = 9131844 | doi =10.1037/0021-843X.106.2.243 cite journal | author = Fox HC, Bergquist KL, Hong KI, Sinha R | title = Stress-induced and alcohol cue-induced craving in recently abstinent alcohol-dependent individuals | journal = Alcohol. Clin. Exp. Res. | volume = 31 | issue = 3 | pages = 395–403 | year = 2007 | month = March | pmid = 17295723 | doi = 10.1111/j.1530-0277.2006.00320.x However, the relationship between negative affect and addiction is not unidirectional. Meaning, while negative affect increase the likelihood of initiation of substance use, the negative affective states produced by withdrawal are the most commonly reported factors for continued use. Key to this concept is the Hedonic Hypothesis which states that individuals initiate use of the substance/behaviour for their pleasurable effects, but then take it compulsively to avoid withdrawal symptoms, resulting in dependence.cite journal | author = Robinson TE, Berridge KC | title = Addiction | journal = Annu Rev Psychol | volume = 54 | issue = | pages = 25–53 | year = 2003 | pmid = 12185211 | doi = 10.1146/annurev.psych.54.101601.145237 Based on this hypothesis it is believed that individuals engaging in risky use of substances/behaviours may be over-responsive to negative stimuli which leads to addiction.
Negative affect has also been a powerful predictor in terms of vulnerability to addiction in adolescents. High risk adolescents have been found to be highly reactive to negative stimuli, which increases their motivation to engage in substance use following a negative emotion-arousing situation.cite journal | author = Randall DM, Cox WM | title = Experimental mood inductions in persons at high and low risk for alcohol problems | journal = Am J Drug Alcohol Abuse | volume = 27 | issue = 1 | pages = 183–7 | year = 2001 | month = February | pmid = 11373034 | doi =10.1081/ADA-100103126 Moreover, it has been established that adolescents high in negative affect are at increased risk for moving from recreational use to problematic use despite a family history of addiction. Furthermore, the trait negative urgency , the propensity to engage in risky behaviour in response to distress (medicine)|distress , is highly predictive of certain aspects of substance abuse in adolescents.cite journal | author = Cyders MA, Smith GT, Spillane NS, Fischer S, Annus AM, Peterson C | title = Integration of impulsivity and positive mood to predict risky behavior: development and validation of a measure of positive urgency | journal = Psychol Assess | volume = 19 | issue = 1 | pages = 107–18 | year = 2007 | month = March | pmid = 17371126 | doi = 10.1037/1040-3590.19.1.107 | url = Early individual differences in emotional differences in reactivity and regualtion underlie the later emergence of the trait 'negative urgency'.cite journal | author = Whiteside SP, Lynam DR | title = The Five Factor Model and impulsivity: using a structural model of personality to understand impulsivity | journal = Personality and Individual Differences | year = 2001 | month = March | volume = 30 | issue = 4 | pages = 669–689 | doi = 10.1016/S0191-8869(00)00064-7
Positive affect
Unlike negative affect, positive affect is related to addiction in both high and low forms. For example, individuals high in positive affect are more likely to engage in risky behaviour, such as drug use. Individuals with high positive affect in response to use are more likely to seek out substances for hedonic reasons. Conversely, low positive affect may prompt initial use due to lack or responsiveness to natural rewards.
Extensive personality research has been done that links positive emotional states to individual differences in risky behaviour. The trait positive urgency , defined as the tendency to engage in risky behaviour under conditions of extreme positive affect, is predictive of substance/behavioural problems that lead to addiction.cite journal | author = Cyders MA, Smith GT | title = Emotion-based dispositions to rash action: positive and negative urgency | journal = Psychol Bull | volume = 134 | issue = 6 | pages = 807–28 | year = 2008 | month = November | pmid = 18954158 | pmc = 2705930 | doi = 10.1037/a0013341 This trait represents an underlying dysregulation in response to extreme affective states and has a direct impact on behaviour. The trait 'positive urgency' has been shown to have a predictive relationship with increases in drinking quantity and alcohol related problems in college, as well as drug use in college.cite journal | author = Zapolski TC, Cyders MA, Smith GT | title = Positive urgency predicts illegal drug use and risky sexual behavior | journal = Psychol Addict Behav | volume = 23 | issue = 2 | pages = 348–54 | year = 2009 | month = June | pmid = 19586152 | pmc = 2709762 | doi = 10.1037/a0014684 Furthermore, this trait provides important information on how positive affect can increase the likelihood of engaging in substance abuse. Another important factor to consider are individual differences in the experience of pleasurable effects brought on by the substance/behaviour. It is reasoned that certain individuals may be more sensitive to the pleasurable effects, and thus experience them with greater intensity, resulting in addiction. For example, over-responsiveness to substance affects has been found in cocaine addicts - an increased response to methylphenidate in the brain regions associated with emotional reactivity and mood.cite journal | author = Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, Gifford A, Hitzemann R, Ding YS, Pappas N | title = Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels | journal = Am J Psychiatry | volume = 156 | issue = 9 | pages = 1440–3 | year = 1999 | month = September | pmid = 10484959 | doi = cite journal | author = Volkow ND | title = The reality of comorbidity: depression and drug abuse | journal = Biol. Psychiatry | volume = 56 | issue = 10 | pages = 714–7 | year = 2004 | month = November | pmid = 15556111 | doi = 10.1016/j.biopsych.2004.07.007 cite journal | author = Volkow ND, Wang GJ, Ma Y, Fowler JS, Wong C, Ding YS, Hitzemann R, Swanson JM, Kalivas P | title = Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction | journal = J. Neurosci. | volume = 25 | issue = 15 | pages = 3932–9 | year = 2005 | month = April | pmid = 15829645 | doi = 10.1523/JNEUROSCI.0433-05.2005 Thus, strong emotional responses that addicted individuals show in response to substances/behaviours might be a results of enhanced sensitivity to their effects.
Individuals differ in the way by which they metabolize substances, such as alcohol ; these positive reinforcing effects are partly predetermined. Individual reactivity to the effects of substances may effect motivation to use. For example, if a person experiences strong positive (and weak negative) effects from a substance, due to their biochemical profile, their expectations of the positive effects from the substance will be heightened. Therefore, increasing their desire for continued use, resulting in dependence. According to this model, the experience of the positive mood enhances implicit attention to substance cues and implicit associations between Reward system|reward and substance use.cite journal | author = Cox WM, Klinger E | title = A motivational model of alcohol use | journal = J Abnorm Psychol | volume = 97 | issue = 2 | pages = 168–80 | year = 1988 | month = May | pmid = 3290306 | doi =10.1037/0021-843X.97.2.168
Interestingly, many addicts report symptoms of anhedonia (i.e., the inability to experience pleasure).cite journal | author = Janiri L, Martinotti G, Dario T, Reina D, Paparello F, Pozzi G, Addolorato G, Di Giannantonio M, De Risio S | title = Anhedonia and substance-related symptoms in detoxified substance-dependent subjects: a correlation study | journal = Neuropsychobiology | volume = 52 | issue = 1 | pages = 37–44 | year = 2005 | pmid = 15942262 | doi = 10.1159/000086176 Results of chronic deviation of the brain's reward set point, which follow a prolonged intoxication, diminish responsiveness to natural positive stimuli. This may result in an over-responsiveness to substance related cues, coupled with an impaired capacity to initiate behaviours in response to natural rewards.cite journal | author = Koob GF, Le Moal M | title = Drug abuse: hedonic homeostatic dysregulation | journal = Science | volume = 278 | issue = 5335 | pages = 52–8 | year = 1997 | month = October | pmid = 9311926 | doi =10.1126/science.278.5335.52 Thus, low positive affect will inhibits the individual's ability to replace drug taking with other rewarding activities. It has also been proposed that during substance dependence the somatic states that guide decision-making are weakened in relation to natural rewards, while at the same time they enhance the emotional response to drug-related stimuli.cite journal | author = Bechara A | title = Risky business: emotion, decision-making, and addiction | journal = J Gambl Stud | volume = 19 | issue = 1 | pages = 23–51 | year = 2003 | pmid = 12635539 | doi =10.1023/A:1021223113233
Compulsive behaviours characterized by addiction are underpinned by two interacting systems: (a) impulsivity, and (b) reflection. Impulsivity is responsible for the rapid signalling of the affective importance of a stimuli. While reflection cognitively evaluates the signal before altering the behavioural response. Dysfunction in impulsivity exaggerates the emotional impact of the drug-related stimuli and attenuates the impact of natural reinforcement. Dysregualtion in reflection results in the inability to override impulsivity, thus resulting in addiction. Under-responsiveness to naturally occurring positive stimuli is a crucial element that biases the individual towards the use of substances/behaviours and away from non-drug alternatives.
Effortful control
Tempermental effortful control is defined as the ability to suppress a dominant response in order to perform a subdominant response.cite journal | author = Rothbart MK, Ellis LK, Rueda MR, Posner MI | title = Developing mechanisms of temperamental effortful control | journal = J Pers | volume = 71 | issue = 6 | pages = 1113–43 | year = 2003 | month = December | pmid = 14633060 | doi =10.1111/1467-6494.7106009 In other words, it is the degree of control the individual has over impulses and emotions; which includes the ability to focus or shift attention. Tempermental effortful control can influence addiction in a number of ways. Low levels of effortful control can render the individual less able to distract themselves from unpleasant feelings or overcome strong affective impulses, resulting in maladaptive responses to distress - such as continued substance use. Low effortful control may also interact with negative and positive affect, predisposing individuals to substance/behavioural use, and impair their ability to control use. A general inability to control affective states may impair the conditioning of behaviour associated with rewards and punishment, increase susceptibility to biasing by substance-related cues, and could tax self-regulatory capacity. Such conditions may render individuals unable to interrupt automatic drug-seeking behaviours. Abnormal levels of positive and negative affect can be increased by low effortful control.cite journal | author = Colder CR, Chassin L | title = Affectivity and impulsivity: Temperament risk for adolescent alcohol involvement | journal = Psychology of Addictive Behaviors | year = 1997 | month = June | volume = 11 | issue = 2 | pages = 83–97 | doi = 10.1037/0893-164X.11.2.83 cite journal | author = Hussong AM, Chassin L | title = The stress-negative affect model of adolescent alcohol use: disaggregating negative affect | journal = J. Stud. Alcohol | volume = 55 | issue = 6 | pages = 707–18 | year = 1994 | month = November | pmid = 7861800 | doi = For example, high positive affect may interact with low effortful control in increasing risk of addiction amongst vulnerable populations.
Gray's reinforcement sensitivity theory
Gray's Reinforcement sensitivity theory (RST) consists of two motivational systems: the Behaviour Inhibition System (BIS) and the Behaviour Activation System (BAS).cite journal | author = Gray JA | title = The psychophysiological basis of introversion-extraversion | journal = Behav Res Ther | volume = 8 | issue = 3 | pages = 249–66 | year = 1970 | month = August | pmid = 5470377 | doi = 10.1016/0005-7967(70)90069-0| url = cite book | author = McNaughton N, Gray ,JA | title = The neuropsychology of anxiety: an enquiry into the function of the septo-hippocampal system | publisher = Oxford University Press | location = Oxford Oxfordshire | year = 2000 | pages = | isbn = 0-19-852270-3 The BIS is responsible for organizing behaviour in response to adverse stimuli. In other words, stimuli associated with punishment or the omission/termination of reward, are believed to underlie anxiety. The purpose of the BIS is to initiate behaviour inhibition, or interrupt ongoing behaviour, while the BAS is sensitive to stimuli that signal reward and/or relief from punishment (impusivity). In accordance with the RST, an association was found between people with extreme scores in BIS/BAS and adjustment problems. BIS and BAS reactivity correspond with individual trait differences in positive affect and negative affect - The BAS is associated with trait impulsivity and positive affect, while the BIS is associated with trait negative affect.cite journal | author = Campbell-Sills L, Liverant GI, Brown TA | title = Psychometric evaluation of the behavioral inhibition/behavioral activation scales in a large sample of outpatients with anxiety and mood disorders | journal = Psychol Assess | volume = 16 | issue = 3 | pages = 244–54 | year = 2004 | month = September | pmid = 15456380 | doi = 10.1037/1040-3590.16.3.244 cite journal | author = Jorm AR, Christensen H, Henderson AS, Jacomb PA, Korten AE, Rodgers B | title=Using the BIS/BAS scales to measure behavioural inhibition and behavioural activation: Factor structure, validity and norms in a large community sample | journal = Personality and Individual Differences | year=1998 | month = January | volume = 26 | issue = 1 | pages = 49–58 | doi = 10.1016/S0191-8869(98)00143-3 For instance, it has been postulated that high BIS is related to anxiety, while high BAS is related to conduct disorders or impulsivity.cite journal | author = Quay HC | title = Inhibition and attention deficit hyperactivity disorder | journal = J Abnorm Child Psychol | volume = 25 | issue = 1 | pages = 7–13 | year = 1997 | month = February | pmid = 9093895 | doi =10.1023/A:1025799122529
According to this model substance abuse problems may arise under two different personality traits: low BIS and high BAS. Since the BAS promotes the individual to pursue actions that may result in reward, BAS sensitivity is involved in the initiation of addiction. Significant associations have been found between high BAS such as alcohol misuse in school girls, hazardous drinking in men, illicit drug abuse, and tobacco use. BAS sensitivity is a significant predictor of reactivity to substance cues, or cravings.cite journal | author = Franken IHA, Muris P | title = BIS/BAS personality characteristics and college students' substance use|journal=Personality and Individual Differences | year = 2006 | volume = 40 | issue = 7 | pages = 1497–1503 | doi = 10.1016/j.paid.2005.12.005 cite journal | author = Genovese JE, Wallace D | title = Reward sensitivity and substance abuse in middle school and high school students | journal = J Genet Psychol | volume = 168 | issue = 4 | pages = 465–9 | year = 2007 | month = December | pmid = 18232522 | doi = 10.3200/GNTP.168.4.465-469 cite journal | author = Kimbrel NA, Nelson-Gray RO, Mitchell JT | title = Reinforcement sensitivity and maternal style as predictors of psychopathology | journal = Personality and Individual Differences | year = 2007 | month = April | volume = 42 | issue = 6 | pages = 1139–1149 | doi = 10.1016/j.paid.2006.06.028 cite journal | author = Knyazev GG | title = Behavioural activation as predictor of substance use: mediating and moderating role of attitudes and social relationships | journal = Drug Alcohol Depend | volume = 75 | issue = 3 | pages = 309–21 | year = 2004 | month = September | pmid = 15283952 | doi = 10.1016/j.drugalcdep.2004.03.007 cite journal | author = Loxton NJ, Dawe S | title = Reward and punishment sensitivity in dysfunctional eating and hazardous drinking women: associations with family risk | journal = Appetite | volume = 47 | issue = 3 | pages = 361–71 | year = 2006 | month = November | pmid = 16846665 | doi = 10.1016/j.appet.2006.05.014 cite journal | author = Loxton NJ, Dawe S | title = How do dysfunctional eating and hazardous drinking women perform on behavioural measures of reward and punishment sensitivity? | journal = Personality and Individual Differences | year = 2007 | month = April | volume = 42 | issue = 6 | pages = 1163–1172 | doi = 10.1016/j.paid.2006.09.031cite journal | author = O’Connor RM, Stewart SH, Watt MC|title=Distinguishing BAS risk for university students' drinking, smoking, and gambling behaviors|journal=Personality and Individual Differences | year = 2009 | month = March | volume = 46 | issue = 4 | pages = 514–519 | doi = 10.1016/j.paid.2008.12.002 cite journal | author = Pardo Y, Aguilar R, Molinuevo B, Torrubia R | title = Alcohol use as a behavioural sign of disinhibition: evidence from J.A. Gray's model of personality | journal = Addict Behav | volume = 32 | issue = 10 | pages = 2398–403 | year = 2007 | month = October | pmid = 17407802 | doi = 10.1016/j.addbeh.2007.02.010 Conversely, BIS sensitivity is involved in avoiding negative situations or affect (such as withdrawal). Low BIS has been positively associated with continuing the addiction to relieve feelings of withdrawal, or for continued use to alleviate negative affect.
Model of impulsivity
The model of impulsivity states that individuals high in impulsivity are at greater risk of addictive behaviours. The model proposes a two dimensional trait characteristic for the initiation and continuation of substance/behavioural abuse:
Reward Drive (RD) - reflects individual differences in sensitivities to incentive motivation and engagement of addictive behaviour when reward cues are detected.cite journal | author = Dawe S, Loxton NJ | title = The role of impulsivity in the development of substance use and eating disorders | journal = Neurosci Biobehav Rev | volume = 28 | issue = 3 | pages = 343–51 | year = 2004 | month = May | pmid = 15225976 | doi = 10.1016/j.neubiorev.2004.03.007
Rash Impulsiveness (RI) - reflecting individual differences in the ability to modify the addictive behaviour due to negative consequences. Individuals high in RI are oblivious or insensitive to the negative consequences as a result of addictive behaviour when engagement is craved.
Both high RD and RI individuals are found to have difficulty in making decisions that have future consequences. Individuals high in RD experience greater reinforcement when initially engaging in the addictive behaviour, and experience stronger conditioned associations with continued use. Individuals high in RI experience greater difficulty resisting craving (withdrawal)|craving s even in the face of negative consequences. Some moderators of RD and RI on the severity of addiction are stress and negative affect (such as feeling depressed).cite journal | author = Koob GF, Le Moal M | title = Drug addiction, dysregulation of reward, and allostasis | journal = Neuropsychopharmacology | volume = 24 | issue = 2 | pages = 97–129 | year = 2001 | month = February | pmid = 11120394 | doi = 10.1016/S0893-133X(00)00195-0 That is, individuals high in RD/RI who also experience high levels of negative affect or stress, present more severe addictive behaviours. For example, if an individual is experiencing emotional distress, the distress experienced may lessen impulse control if they believe that engaging in addictive behaviour will decrease negative affect. According to this model, adolescents who are high in RI are at greater risk for developing addictions. Interestingly, low RI has been shown to moderate some of the risk of addiction due to family history.cite journal | author = Brook JS, Kessler RC, Cohen P | title = The onset of marijuana use from preadolescence and early adolescence to young adulthood | journal = Dev. Psychopathol. | volume = 11 | issue = 4 | pages = 901–14 | year = 1999 | pmid = 10624731 | doi =10.1017/S0954579499002370 cite journal | author = Lynskey MT, Fergusson DM, Horwood LJ | title = The origins of the correlations between tobacco, alcohol, and cannabis use during adolescence | journal = J Child Psychol Psychiatry | volume = 39 | issue = 7 | pages = 995–1005 | year = 1998 | month = October | pmid = 9804032 | doi =10.1111/1469-7610.00402 cite journal | author = King KM, Chassin L | title = Mediating and moderated effects of adolescent behavioral undercontrol and parenting in the prediction of drug use disorders in emerging adulthood | journal = Psychol Addict Behav | volume = 18 | issue = 3 | pages = 239–49 | year = 2004 | month = September | pmid = 15482079 | doi = 10.1037/0893-164X.18.3.239 cite journal | author = Tarter RE, Kirisci L, Habeych M, Reynolds M, Vanyukov M | title = Neurobehavior disinhibition in childhood predisposes boys to substance use disorder by young adulthood: direct and mediated etiologic pathways | journal = Drug Alcohol Depend | volume = 73 | issue = 2 | pages = 121–32 | year = 2004 | month = February | pmid = 14725951 | doi =10.1016/j.drugalcdep.2003.07.004 However, high RI for individual without a family history of addiction has been related to poor decision-making.
Cloninger's tri-dimensional personality theory
Cloninger's Tri-Dimensional Personality Theory states that personality comprises three genetically independent dimensions:cite journal | author = Cloninger CR | title = A systematic method for clinical description and classification of personality variants. A proposal | journal = Arch. Gen. Psychiatry | volume = 44 | issue = 6 | pages = 573–88 | year = 1987 | month = June | pmid = 3579504 | doi =10.1001/archpsyc.1987.01800180093014
Novelty seeking (NS) - tendency towards exploration and intense exhilaration in response to novel stimuli
Harm avoidance (HA) - intense response to adverse stimuli and learned inhibited behaviour to avoid punishment
Reward dependence (RD) - resistance to extinction of previously rewarded behaviour.
Each personality dimension lies on a spectrum ranging from low to high. For example, individuals high in NS are impulsive, while individual's low in NS are reflective. Interactions between each of these three personality dimensions lead to different responses to novelty, punishment and rewards.
This model was extended to alcohol use disorders proposing that individuals with alcohol use disorders have extreme temperaments (i.e. are very high or very low in NS, HA, and RD).cite journal | author = Howard MO, Kivlahan D, Walker RD | title = Cloninger's tridimensional theory of personality and psychopathology: applications to substance use disorders | journal = J. Stud. Alcohol | volume = 58 | issue = 1 | pages = 48–66 | year = 1997 | month = January | pmid = 8979213 | doi = This model proposes that alcoholics can be classified in two groups based on the combinations of their three personality dimensions:
Type I alcoholics have a late onset of alcohol related problems, experience guilt and fear associated with consumption, lose control once drinking is initiated, engage in alcohol related antisocial conduct, and rarely exhibit spontaneous alcohol-seeking behaviour.cite journal | author = Cloninger CR | title = Neurogenetic adaptive mechanisms in alcoholism | journal = Science | volume = 236 | issue = 4800 | pages = 410–6 | year = 1987 | month = April | pmid = 2882604 | doi = 10.1126/science.2882604| url = | bibcode = 1987Sci...236..410C Type I alcoholics are thought to be low in NS and high in HA and RD, exhibiting behaviors that are motionally dependent, rigid, perfectionistic, anxious, quiet, patient, and introverted.
Type II alcoholics have an earlier onset of alcohol related problems, less ability to abstain from alcohol, more frequent alcohol-related antisocial behaviour, less loss of control once drinking commenced, and less guilt or fear associated with drinking. These individuals are high in NS, and low in HA and RD, which means they may be typically aggressive, impulsive, active, talkative, and impatient.
References
Reflist|colwidth=35em
Further reading
Wiktionary|addiction|-holism
Cite journal |date=July 16, 2007 |author=Lemonick, Michael D |title=How We Get Addicted |journal= Time (magazine)|Time |volume=170 |issue=38 |url= http://www.time.com/time/magazine/article/0,9171,1640436,00.html |accessdate=7 September 2010 |postscript=| archiveurl= http://web.archive.org/web/20100902001053/ http://www.time.com/time/magazine/article/0,9171,1640436,00.html| archivedate= 2 September 2010 | deadurl= no http://www.time.com/time/covers/0,16641,20070716,00.html Cover July 16, 2007 (note: cover provided to clarify date discrepancy from article link)
Cite document |date=2008 |author=Martin, Paul |title=Sex, Drugs & Chocolate: The Science of Pleasure |place=London |publisher=Fourth Estate |isbn=978-0-00-712708-5
Cite journal |date=May 5, 1997 |author=Nash-Alice, Madeleine J |title=Addicted: Why do people get hooked? |journal= Time (magazine)|Time |issue=18 |pages=52–58 |url= http://www.time.com/time/magazine/article/0,9171,986282,00.html Dubious|date=March 2011
Cite book |year=2004 |author= Andrew Weil|Weill, Andrew & Rosen, Winifred |title=From Chocolate to Morphine: Everything you need to know about mind-altering drugs |place=Boston & New York |publisher= Houghton Mifflin Harcourt|Houghton Mifflin |isbn=0-618-48379-9 |url= http://books.google.com/? id=p6zyPxi4PYoC& printsec=frontcover& dq=%22chocolate+to+morphine%22& q |accessdate=07 September 2010 Dubious|date=March 2011
