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DMC may refer to:
Algorithmics- Diffusion Monte Carlo, a method that utilizes a Green function to solve the Schrödinger equation
- Dynamic Markov Compression, a general purpose statistical data compression algorithm
- Dynamic Matrix Control, an approach for multi-input/output model predictive control
Media and entertainment- Digital mixing console, an electronic device for combining, routing, and changing the dynamics of digital audio samples
- Darryl McDaniels, a member of hip hop group Run-DMC
- Devil May Cry (series), a video game series
- Detroit Metal City, a manga series.
- Disco Mix Club, an organization known for its yearly world DJ championships
- DMC.TV, Dhamma Media Channel
- Deathmatch Classic, a Half-Life mod
- Duel Masters Civilisations, a fan-made program for playing the Duel Masters trading card game online
Motor vehicles- DeLorean Motor Company, makers of the distinctive DeLorean DMC-12 sports car
- Daelim Motor Company, a South Korean motorcycle (<250cc) and motorscooter manufacturer
- A series of snowcats made by the Logan Machine Company
Organizations- Digital Media Center, German based software company
- Destination Management Company, a company that specializes in the organization of meetings and events
- Detroit Medical Center, a non-profit corporation that operates certain hospitals in southeast Michigan
- Dipolog Medical Centre Foundation College, Inc, Dipolog City, Philippines
- Data Monitoring Committees, groups that review clinical trials to ensure safety of trial participants
- Defence Munitions centre, of the UK military
- Dhaka Medical College, Bangladesh.
Other uses- Disaster Monitoring Constellation, a set of imaging satellites run by DMC International Imaging.
- Digital Magnetic Compass, a magnetic compass without moving parts.
- Dimethyl carbonate, a chemical compound.
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