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Biography
About|the hygiene product|the Kate Nash song|Mouthwash (song)|the ska-punk band|Mouthwash (band) Mouthwash or mouth rinse is a product used to enhance oral hygiene . Some manufacturers of mouthwash claim that antiseptic and anti-plaque mouth rinse kill the Dental plaque|bacterial plaque causing Dental caries|cavities , gingivitis , and bad breath . Anti-cavity mouth rinse uses fluoride to protect against tooth decay . It is, however, generally agreed that the use of mouthwash does not eliminate the need for both toothbrush|brushing and flossing .cite journal |pmid=17138709 |year=2006 |last1=Gunsolley |first1=JC |title=A meta-analysis of six-month studies of antiplaque and antigingivitis agents |volume=137 |issue=12 |pages=1649–57 |journal=Journal of the American Dental Associationcite journal |pmid=2366142 |year=1990 |last1=Tal |first1=H |last2=Rosenberg |first2=M |title=Estimation of dental plaque levels and gingival inflammation using a simple oral rinse technique |volume=61 |issue=6 |pages=339–42 |journal=Journal of periodontology http://www.msnbc.msn.com/id/6799764 Listerine no replacement for flossing? As per the American Dental Association , regular brushing and proper flossing are enough in most cases although the ADA has placed its Seal of Approval on many mouthwashes containing alcohol (in addition to regular dental check-ups).https://www.ada.org/prof/resources/pubs/jada/patient/patient_01.pdf Simple Routine for Basic Oral Care
Mouthwash may also be used to help remove mucus and food particles deeper down in the throat.Citation needed|date=November 2008 Alcoholic and strongly flavored mouthwash may cause coughing when used for this purpose.
History
The first known references to mouth rinsing is in Ayurveda and Chinese medicine , about 2700 BC, for treatment of gingivitis .Citation needed|date=August 2008 Later, in the ancient Greece|Greek and Ancient Rome|Roman periods, mouth rinsing following mechanical cleansing became common among the upper classes, and Hippocrates recommended a mixture of salt, alum , and vinegar.cite journal |pages=7–14 |doi=10.1111/j.1600-0757.1997.tb00099.x |title=The history of oral hygiene products: How far have we come in 6000 years? |year=1997 |last1=Fischman |first1=Stuart L. |journal=Periodontology 2000 |volume=15 |pmid=9643227 The Jewish Talmud , dating back about 1800 years, suggests a cure for gum ailments containing "dough water" and olive oil.cite journal |pmid=12389360 |year=2002 |last1=Shifman |first1=A |last2=Orenbuch |first2=S |last3=Rosenberg |first3=M |title=Bad breath--a major disability according to the Talmud |volume=4 |issue=10 |pages=843–5 |journal=The Israel Medical Association journal
Anton van Leeuwenhoek , the famous 17th century microscopist , discovered living organisms (living, because they were motile) in deposits on the teeth (what we now call dental plaque ). He also found organisms in water from the canal next to his home in Delft. He experimented with samples by adding vinegar or brandy and found that this resulted in the immediate immobilization or killing of the organisms suspended in water. Next he tried rinsing the mouth of himself and somebody else with a mouthwash containing vinegar or brandy and found that living organisms remained in the dental plaque. He concluded& mdash;correctly& mdash;that the mouthwash either did not reach, or was not present long enough, to kill the plaque organisms.Citation needed|date=September 2007 That remained the state of affairs until the late 1960s when Harald Loe (at the time a professor at the Royal Dental College in Aarhus , Denmark ) demonstrated that a chlorhexidine compound could prevent the build-up of dental plaque. The reason for chlorhexidine effectiveness is that it strongly adheres to surfaces in the mouth and thus remains present in effective concentrations for many hours.cite journal |pmid=4575037 |year=1972 |last1=Budtz-Jörgensen |first1=E |last2=Löe |first2=H |title=Chlorhexidine as a denture disinfectant in the treatment of denture stomatitis |volume=80 |issue=6 |pages=457–64 |journal=Scandinavian journal of dental research
Since then commercial interest in mouthwashes has been intense and several newer products claim effectiveness in reducing the build-up in dental plaque and the associated severity of gingivitis (inflammation of the gums), in addition to fighting bad breath. Many of these solutions aim to control the Volatile Sulfur Compound (VSC)-creating anaerobic bacteria that live in the mouth and excrete substances that lead to bad breath and unpleasant mouth taste.cite journal |pmid=8133414 |year=1994 |last1=Bosy |first1=A |last2=Kulkarni |first2=GV |last3=Rosenberg |first3=M |last4=McCulloch |first4=CA |title=Relationship of oral malodor to periodontitis: Evidence of independence in discrete subpopulations |volume=65 |issue=1 |pages=37–46 |journal=Journal of periodontologycite journal |pages=256–79 |doi=10.1034/j.1600-0757.2002.280111.x |title=Microbiology and treatment of halitosis |year=2002 |last1=Loesche |first1=Walter J. |last2=Kazor |first2=Christopher |journal=Periodontology 2000 |volume=28 |pmid=12013345
Usage
Common use involves rinsing the mouth with about 20 milliliter|ml (2/3 fluid ounce|fl oz ) of mouthwash two times a day after brushing. The wash is typically swished or gargling|gargled for about half a minute and then spat out. In some brands, the expectorate is stained, so that one can see the bacteria and debris.cite journal |pmid=8794967 |year=1996 |last1=Kozlovsky |first1=A |last2=Goldberg |first2=S |last3=Natour |first3=I |last4=Rogatky-Gat |first4=A |last5=Gelernter |first5=I |last6=Rosenberg |first6=M |title=Efficacy of a 2-phase oil: Water mouthrinse in controlling oral malodor, gingivitis, and plaque |volume=67 |issue=6 |pages=577–82 |journal=Journal of periodontologycite journal |pmid=1552460 |year=1992 |last1=Rosenberg |first1=M |last2=Gelernter |first2=I |last3=Barki |first3=M |last4=Bar-Ness |first4=R |title=Day-long reduction of oral malodor by a two-phase oil:water mouthrinse as compared to chlorhexidine and placebo rinses |volume=63 |issue=1 |pages=39–43 |journal=Journal of periodontology Some may suggest that it is probably advisable to use mouthwash at least an hour after brushing with toothpaste when the toothpaste contains sodium lauryl sulfate , since the anionic compounds in the SLS toothpaste can deactivate cationic agents present in the mouthrinse.cite journal |pages=72–9 |doi=10.1038/scientificamerican0402-72 |title=The Science of Bad Breath |year=2002 |last1=Rosenberg |first1=Mel |journal=Scientific American |volume=286 |issue=4 |pmid=11905111 However, many would disagree with this hypothesis; in fact, many of the popular mouthwashes contain sodium lauryl sulfate as an ingredient (e.g., Listerine Total Care).Citation needed|date=September 2011
Active ingredients
Active ingredient s in commercial brands of mouthwash can include thymol , eucalyptol ,cite journal |pages=1218–28 |doi=10.1902/jop.2007.060269 |title=The Long-Term Effect of a Mouthrinse Containing Essential Oils on Dental Plaque and Gingivitis: A Systematic Review |year=2007 |last1=Stoeken |first1=Judith E. |last2=Paraskevas |first2=Spiros |last3=Van Der Weijden |first3=Godefridus A. |journal=Journal of Periodontology |volume=78 |issue=7 |pmid=17608576 hexetidine , methyl salicylate , menthol , chlorhexidine gluconate ,cite journal |pages=359–70 |doi=10.1016/j.jdent.2007.01.007 |title=The effect of different formulations of chlorhexidine in reducing levels of mutans streptococci in the oral cavity: A systematic review of the literature |year=2007 |last1=Ribeiro |first1=L |last2=Hashizume |first2=L |last3=Maltz |first3=M |journal=Journal of Dentistry |volume=35 |issue=5 |pmid=17391828 benzalkonium chloride , cetylpyridinium chloride ,cite journal |pmid=16348211 |year=1990 |last1=Goldberg |first1=S |last2=Konis |first2=Y |last3=Rosenberg |first3=M |title=Effect of cetylpyridinium chloride on microbial adhesion to hexadecane and polystyrene |volume=56 |issue=6 |pages=1678–82 |pmc=184492 |journal=Applied and environmental microbiology methylparaben , hydrogen peroxide , domiphen bromide and sometimes fluoride ,cite journal |pmid=12734021 |year=2003 |last1=Levy |first1=SM |title=An update on fluorides and fluorosis |volume=69 |issue=5 |pages=286–91 |journal=Journal (Canadian Dental Association) enzymes , and calcium . Ingredients also include water, sweeteners such as sorbitol , sucralose , Saccharin|sodium saccharin , and xylitol (which doubles as a bacterial inhibitor).cite journal |pages=23–31 |doi=10.1159/000016492 |title=Effects of Mouth Rinses with Xylitol and Fluoride on Dental Plaque and Saliva |year=1999 |last1=Giertsen |first1=E. |last2=Emberland |first2=H. |last3=Scheie |first3=A. Aa. |journal=Caries Research |volume=33 |pmid=9831777 |issue=1
Sometimes a significant amount of ethanol|alcohol (up to 27% vol) is added,cite journal |first1=Dirk W |last1=Lachenmeier |first2=Andrea |last2=Keck-Wilhelm |first3=Anne |last3=Sauermann |first4=Gerd |last4=Mildau |year=2008 |title=Safety Assessment of Alcohol-Containing Mouthwashes and Oral Rinses |journal=SOFW Journal |volume=134 |issue=10 |pages=70–8 |url= http://www.sofw.com/index/sofw_en/sofw_en_archive.html? cosearch=mouthwashes& cosearch_sa=mouthwashes& costart=& date_from%5BY%5D=2004& date_from%5Bm%5D=1& date_until%5BY%5D=2008& date_until%5Bm%5D=10& do_search_sa=1& naid=3193 as a carrier for the flavor , to provide "bite".cite journal |last1=Pader |first1=M. |title=Oral rinses |journal= Cosmetics & Toiletries |month=October |year=1994 |volume=109 |issue=10 |pages=59–68 |issn=0361-4387Unreliable medical source|date=September 2011 Because of the alcohol content, it is possible to fail a breathalyzer test after rinsing although breath alcohol levels return to normal after 10mins;Citation needed|date=September 2011 in addition, alcohol is a drying agent and may worsen chronic bad breath.Citation needed|date=September 2011 Recently, the possibility that the alcohol used in mouthrinses acts as a carcinogen was raised, but there is to date no scientific consensus on the issue.cite journal |pmid=12956348 |year=2003 |last1=Cole |first1=P |last2=Rodu |first2=B |last3=Mathisen |first3=A |title=Alcohol-containing mouthwash and oropharyngeal cancer: A review of the epidemiology |volume=134 |issue=8 |pages=1079–87 |journal=Journal of the American Dental Associationcite journal |pmid=14990877 |year=2004 |last1=Carretero Peláez |first1=MA |last2=Esparza Gómez |first2=GC |last3=Figuero Ruiz |first3=E |last4=Cerero Lapiedra |first4=R |title=Alcohol-containing mouthwashes and oral cancer. Critical analysis of literature |volume=9 |issue=2 |pages=120–3, 116–20 |journal=Medicina oralcite journal |doi=10.1186/1745-6673-3-26 |title=Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity |year=2008 |last1=Lachenmeier |first1=Dirk W |journal=Journal of Occupational Medicine and Toxicology |volume=3 |pmid=19014531 |pmc=2596158 |pages=26 Commercial mouthwashes usually contain a preservative such as sodium benzoate to preserve freshness once the container has been opened. Many newer brands are alcohol-free and contain odor-elimination agents such as oxidizers, as well as odor-preventing agents such as zinc ion to keep future bad breath from developing.Citation needed|date=September 2007
Alternative mouthwash ingredients
A salt mouthwash is a home treatment for mouth infections and/or injuries, or post extraction, and is made by dissolving a teaspoon of Edible salt|salt in a cup of warm water.
Vodka, gin and other hard liquors (with alcohol content of 35% or more) can be used as an alternative to Listerine, especially if one is looking for a mouthwash with only natural ingredients. Flavored spirits, such as London dry gin, work especially well as the flavorings can mask the alcohol smell. However, such use can be problematic in households with children.
Recently, the use of herbal mouthwashes such as Salvadora persica|persica is increasing, due to the perceived discoloration effects and unpleasant taste of chlorhexidine.cite journal |last1=Salehi |first1=P. |last2=Momeni Danaie |first2=Sh. |year=2006 |title=Comparison of the antibacterial effects of persica mouthwash with chlorhexidine on streptococcus mutans in orthodontic patients |journal=DARU Journal of Pharmaceutical Sciences |volume=14 |issue=4 |pages=178–82 |url= http://journals.tums.ac.ir/abs/3015 Research has also indicated that Oil_pulling#Scientific_assessment|sesame and sunflower oils are alternatives to chlorhexidine. http://iadr.confex.com/iadr/2008Toronto/techprogram/abstract_105440.htm http://www.johcd.org/pdf/Effect_of_Oil_Pulling_on_Plaque_and_Gingivitis.pdf
Other products like hydrogen peroxide have been tried out as stand-alonecite journal |pages=57–65 |doi=10.1902/jop.2004.75.1.57 |title=Efficacy of a Fluoridated Hydrogen Peroxide-Based Mouthrinse for the Treatment of Gingivitis: A Randomized Clinical Trial |year=2004 |last1=Hasturk |first1=Hatice |last2=Nunn |first2=Martha |last3=Warbington |first3=Martha |last4=Dyke |first4=Thomas E. Van |journal=Journal of Periodontology |volume=75 |pmid=15025217 |issue=1 and in combination with chlorhexidine, due to some inconsistent results regarding its usefulness.cite journal |pages=31–4 |doi=10.1111/j.1399-302X.2004.00189.x |title=Comparative analysis of the antibacterial effects of combined mouthrinses on Streptococcus mutans |year=2005 |last1=Menendez |first1=A. |last2=Li |first2=F. |last3=Michalek |first3=S. M. |last4=Kirk |first4=K. |last5=Makhija |first5=S. K. |last6=Childers |first6=N. K. |journal=Oral Microbiology and Immunology |volume=20 |pmid=15612942 |issue=1
Another study has demonstrated that daily use of an alum -containing mouthrinse was safe and produced a significant effect on plaque that supplemented the benefits of daily toothbrushing.cite journal |pmid=8710717 |year=1996 |last1=Putt |first1=MS |last2=Kleber |first2=CJ |last3=Smith |first3=CE |title=Evaluation of an alum-containing mouthrinse in children for plaque and gingivitis inhibition during 4 weeks of supervised use |volume=18 |issue=2 |pages=139–44 |journal=Pediatric dentistry
However, many studies acknowledge that Chlorhexidine remains the most effective mouthwash when used on an already clean tooth surface or immediately after surgery. As chlorhexidine has difficulty in penetrating plaque biofilm, other mouthwashes may be more effective where pre-existing plaque is present. One side-effect as noted on the label is the staining of the teeth will occur for prolong usage.Citation needed|date=September 2011
Compounding
Custom mouthwashes, called " magic mouthwash " may be prescribed by dentists for post oral surgeries. Variations are common, and some are done with Over-the-counter drug|over-the-counter products.Citation needed|date=September 2011
Health risks
A literature review by Michael McCullough and Camile Farah, published in the Australian Dental Journal in 2008, focused on a possible connection between mouthwashes that contain alcohol, and an increased risk of oral cancer. quote|There is now sufficient evidence to accept the proposition that developing oral cancer is increased or contributed to by the use of alcohol-containing mouthwashes. Whilst many of these products may have been shown to be effective in penetrating oral microbial biofilms in vitro and reducing oral bacterial load, it would be wise to restrict their use to short-term therapeutic situations if needed. Perhaps the use of mouthwashes that do not contain alcohol may be equally effective. Further, mouthrinses should be prescribed by dentists, like any other medication. There may well be a reason for the use of alcohol-containing mouthrinses, but only for a particular situation and for a limited and controlled period of time. As such, patients should be provided with written instructions for mouthwash use, and mouthwash use should be restricted to adults for short durations and specific, clearly defined reasons. It is the opinion of the authors that, in light of the evidence currently available of the association of alcohol-containing mouthwashes with the development of oral cancer, it would be inadvisable for oral healthcare professionals to recommend the long-term use of alcohol-containing mouthwashes.|McCullough and Farah| Australian Dental Journal cite journal |doi=10.1111/j.1834-7819.2008.00070.x |title=The role of alcohol in oral carcinogenesis with particular reference to alcohol-containing mouthwashes |year=2008 |last1=McCullough |first1=MJ |last2=Farah |first2=CS |journal=Australian Dental Journal |volume=53 |issue=4 |pages=302–5 |pmid=19133944McCullough and Farah also state that the risk of acquiring cancer rises almost five times for users of alcohol-containing mouthwash who neither smoke nor drink (with a higher rate of increase for those who do).Farah, C; McIntosh, L; McCullough, M (2009). "Mouthwashes". Australian Prescriber , 32:162-4. Available at http://www.australianprescriber.com/magazine/32/6/162/4/ australianprescriber.com In addition, the authors highlight side effects from several mainstream mouthwashes that included dental erosion and accidental poisoning of children.
The review garnered media attentioncite news | last = Weaver | first = Clair | coauthors = | title = Mouthwash linked to cancer | work = Daily Telegraph | pages = | publisher = News Ltd | date = 11 January 2009 | url = http://www.news.com.au/dailytelegraph/story/0,22049,24896583-5001021,00.html | accessdate = 11 January 2009 and conflicting opinions from other researchers. Yinka Ebo of Cancer Research UK disputed the findings, concluding that "there is still not enough evidence to suggest that using mouthwash that contains alcohol will increase the risk of mouth cancer".cite web|last=Ebo|first=Yinka|title=Does mouthwash cause cancer? |url= http://scienceblog.cancerresearchuk.org/2009/01/14/does-mouthwash-cause-cancer/|publisher= Cancer Research UK |accessdate=20 June 2009|date=14 January 2009 Studies conducted in 1985,cite journal |pmid=3859544 |year=1985 |last1=Mashberg |first1=A |last2=Barsa |first2=P |last3=Grossman |first3=ML |title=A study of the relationship between mouthwash use and oral and pharyngeal cancer |volume=110 |issue=5 |pages=731–4 |journal=Journal of the American Dental Association 1995,cite journal |doi=10.1016/S0194-5998(95)70114-1 |title=Oral cancer and mouthwash use: Evaluation of the epidemiologic evidence |year=1995 |last1=Elmore |first1=J |last2=Horwitz |first2=R |journal=Otolaryngology - Head and Neck Surgery |volume=113 |issue=3 |pages=253–61 |pmid=7675486 and 2003cite journal |pmid=12956348 |url= http://jada.ada.org/cgi/content/full/134/8/1079 |year=2003 |last1=Cole |first1=P |last2=Rodu |first2=B |last3=Mathisen |first3=A |title=Alcohol-containing mouthwash and oropharyngeal cancer: A review of the epidemiology |volume=134 |issue=8 |pages=1079–87 |journal=Journal of the American Dental Association did not support an association between alcohol-containing mouth rinses and oral cancer. Andrew Penman, chief executive of The Cancer Council New South Wales , called for further research on the matter.cite news |first=Clair |last=Weaver |authorlink= |coauthors= |title=Mouthwash linked to cancer |url= http://www.news.com.au/dailytelegraph/story/0,22049,24896583-5001021,00.html |work= |publisher=The Daily Telegraph |date=January 11, 2009 |accessdate=12 January 2009 In a March 2009 brief, the American Dental Association said "the available evidence does not support a connection between oral cancer and alcohol-containing mouthrinse". http://www.ada.org/sections/professionalResources/pdfs/topics_cancer_brief_mouthrinses.pdf Science brief on alcohol-containing mouthrinses and oral cancer, American Dental Association , March 2009
Mouthwashes containing cetylpyridinium chloride are also associated with loss of taste sensation and brown discolouration of the teeth.Citation needed|date=September 2011
Brands
Astring-O-Sol
Colgate (toothpaste)|Colgate cite web
| last = Colgate-Palmolive | first = | authorlink = | coauthors = | title = Colgate Plax Mouthwash | work = | publisher = | date = | url = http://www.colgate.com.au/app/Colgate/AU/OC/Products/OverTheCounter/Name.cvsp | format = | doi = | accessdate = 6 July 2009
Corsodyl
Dentyl pH
Meridol
Listerine
Oral-B cite web
| last = Procter & Gamble | first = | authorlink = | coauthors = | title = Oral-B | work = | publisher = | date = | url = http://www.oralb.com/ | format = | doi = | accessdate = 8 July 2009
Sarakan
Scope (mouthwash)
Tantum verde
See also
Portal|Dentistry
Kunzea ericoides
Leptospermum scoparium
Magic mouthwash
Mucositis
Period-after-opening symbol
Sodium fluoride
Sodium monofluorophosphate
Notes and references
Reflist
External links
http://www.msnbc.msn.com/id/17011346/ Article on Bad-Breath Prevention Products – from MSNBC
http://www.unboundmedicine.com/medline/ebm/record/15794454/abstract/Use_of_a_novel_group_of_oral_malodor_measurements_to_evaluate_an_anti_oral_malodor_mouthrinse TriOralTM in_humans Clinical Study on Anti-Oral Malodor Mouthrinse – from Unbound Medline
PeriodontologyThroat preparationsDosage forms|state=showRoutes of administration Category:Dentifrices Category:Oral hygiene Category:Drug delivery devices Category:Dosage forms