Alphonse Rio (1873-1949), French politician and minister in the French Third Republic
Michel Rio (b. in 1945), French writer and novelist
Patrice Rio (b. in 1948), former French footballer
Music
Rio (album)| Rio (album) , a 1982 album by the new wave/rock group Duran Duran
* Rio (song)|"Rio" (song) , the title song from the above Duran Duran album
Rio (Lee Ritenour album) , a 1979 jazz album by Lee Ritenour
Rio (Keith Jarrett album)| Rio (Keith Jarrett album) , a 2011 jazz album by Keith Jarrett
Los del Rio , the Spanish music duo that gained international fame for their 1995 song "Macarena"
Rock in Rio , a series of music festivals held in Brazil and Portugal
Rock in Rio (album)| Rock in Rio (album) , a 2001 live album recorded in Brazil by the rock group Iron Maiden
Rush in Rio , a 2003 live album by the rock group Rush
RIO, for Rock in Opposition , a musical movement in the 1970s
"Rio", a song by Michael Nesmith which appears on his 1977 album From a Radio Engine to the Photon Wing
Rio (Aterciopelados album)| Rio (Aterciopelados album) , 2008 album by the band Aterciopelados
R.I.O. , a german danceband
Technology
Rio (digital audio players) , a brand name of a line of digital audio players
RIO - Reconfigurable Input/Output found in devices such as the CompactRIO
rio (windowing system) , the windowing system for Plan 9 from Bell Labs operating system
Kyocera Rio , or Kyocera E3100, a mobile phone
Winsock#Updates_in_Windows_8|Winsock RIO extensions , part of the Winsock network API
Organizations
Rio All Suite Hotel and Casino , a resort in Las Vegas, USA, that opened in 1990
Rio Tinto Group , a multinational mining and resources group founded in 1873
Rio Group , founded 1986, an international organization of Latin American states
Rio Convention, one of several commonly used "Rio" nicknames for the 1992 Convention on Biological Diversity
rio, pronunciation of RHIO, Regional Health Information Organization , a type of organization whose purpose is integration and information exchange among healthcare stakeholders
Transportation
Avian Rio , a British hang glider
Ford Del Rio , a 1950s station wagon made by Ford Motor Company
Kia Rio , a 2000s subcompact car made by Kia Motors
Panther Rio , a 1970s luxury sedan made by British car makers Panther Westwinds
RIO, the International Air Transport Association airport code|IATA airport code for all airports near Rio de Janeiro
Rio Models , diecast miniature cars made in Italy
Politics
The Rio Protocol of 1942, which temporarily settled a border war between Peru and Ecuador
Rio Declaration on Environment and Development , a 1992 global sustainable development plan
Rio Treaty or Rio Pact of 1947, more formally known as the Inter-American Treaty of Reciprocal Assistance
Fiction
Rio (1939 film)| Rio (1939 film) , starring Basil Rathbone
Rio (film)| Rio (film) , an 2011 animated film from 20th Century Fox and Blue Sky Studios
* Angry Birds Rio , an edition of the game Angry Birds tying into the release of Rio
Rio (Shaman King) , a character in the anime series Shaman King
Rio Hinayama, a List of characters in To Heart#Rio Hinayama|character in To Heart , a 1997 visual novel
Rio, a Characters of NX Files#Rio|character in the web-show NX Files , running since 2005
Rio, the Confrontation Beast-Fist Akugata#Rio|main villain from Juken Sentai Gekiranger , a 2007 Japanese tokusatsu television series
Rio (CSI: Miami)|"Rio" (CSI: Miami) , the first episode in Season 5 (September 2006) of the American television program CSI: Miami
Rio: Rainbow Gate , a 2011 anime series based on a pachinko franchise by Tecmo
* Rio 'Rollins' Tachibana, a character who appears in the Rio: Rainbow Gate anime, as well as some titles in the Dead or Alive (series)|Dead or Alive video games.
Other uses
RIO (military), Radar Intercept Officer
RIO is a Railway Investigation Officer (Melbourne, Australia) Victoria Transit Patrol