More Info on TSQSimilar Undetermined MusicSearch Artistopia
Biography
about|the chemical compound|hydroelectric plant|Tianshengqiao Hydroelectric Plantchembox| verifiedrevid = 401616778|ImageFile=TSQ.png|ImageSize=120px|IUPACName= N -(6-Methoxy-8-quinolyl)-4-toluenesulfonamide|OtherNames=|Section1=Chembox Identifiers| ChemSpiderID_Ref = chemspidercite|correct|chemspider| ChemSpiderID = 115530| InChI = 1/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3| InChIKey = HKRNYOZJJMFDBV-UHFFFAOYAJ| StdInChI_Ref = stdinchicite|correct|chemspider| StdInChI = 1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3| StdInChIKey_Ref = stdinchicite|correct|chemspider| StdInChIKey = HKRNYOZJJMFDBV-UHFFFAOYSA-N| CASNo=109628-27-5| PubChem=130606| SMILES = O=S(=O)(c1ccc(cc1)C)Nc2cc(OC)cc3cccnc23|Section2=Chembox Properties| C=17|H=16|N=2|O=3|S=1| Appearance=| Density=| MeltingPt=| BoilingPt=| Solubility=|Section3=Chembox Hazards| MainHazards=| FlashPt=| Autoignition=' 6-Methoxy-(8- p -toluenesulfonamido)quinoline ' (TSQ) is one of the most efficient fluorescent stains for zinc (II). It was introduced by Russian biochemist s Toroptsev and Eshchenko in the early 1970s. The popularity of TSQ as physiological stain rose after seminal works by Christopher Frederickson two decades later.See for example: cite journal | doi = 10.1016/S0006-8993(99)02096-X | author = Suh S W; Jensen K B; Jensen M S; Silva D S; Kesslak P J; Danscher G; Frederickson C J | title = Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains | journal = Brain Research | year = 2000 | volume = 852 | issue = 2 | pages = 274–278 | pmid = 10678753 TSQ forms a 2:1 (ligand-metal) complex with zinc and emits blue light upon Photoelectric Effect|excitation at 365 nanometers. TSQ has been extensively applied for determination of extracellular or intracellular levels of Zn2+ in biological systems, also to study Zn2+ in mossy fiber s of the hippocampus .
